RYR1 c.14761_14762delTTinsAC

RYR1 c.14761_14762delTTinsAC

The RYR1 c.14761_14762delTTinsAC Novallele Genotyping Assay identifies a mutation of the RYR1 gene. The RYR1 gene encodes for a ryanodine receptor found in skeletal muscle. Mutations of the RYR1 gene can be linked to malignant hyperthermia susceptibility, which is triggered by drugs metabolized by the RYR1 pathway. These drugs may include succinylcholine, caffeine, desflurane, enflurane, halothane, or methoxyflurane.


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Product Description

The RYR1 c.14761_14762delTTinsAC Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers and unlabeled probes necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.