HFE c.845G>A

HFE c.845G>A

The HFE c.845G>A Novallele Genotyping Assay identifies a single nucleotide change associated with mutations in the inherited hemochromatosis gene. This specific mutation accounts for approximately 85% of all cases of Type I hemochromatosis. Type I hemochromatosis is linked to disrupted iron regulation throughout the body, which leads to cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure.


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Product Description

The HFE c.845G>A Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers and unlabeled probes necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.