DNMT1 c.1389A>G

DNMT1 c.1389A>G

The DNMT1 c.1389A>G Novallele Genotyping Assay identifies a single nucleotide change associated with the DNMT1 gene. Mutations of the DNMT1 gene are associated with hereditary sensory and autonomic neuropathy (HSAN). HSAN is characterized by dementia, deafness, and sensory problems in the feet. In addition, DNMT1 mutations are also responsible for an increased risk of cancer including cancers of the breast and stomach and certain brain cancers called glioma.


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Product Description

The DNMT1 c.1389A>G Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.