CYP2C19 c.358T>C

CYP2C19 c.358T>C

The CYP2C19 c.358T>C Novallele Genotyping Assay identifies a single nucleotide change of the CYP2C19 gene associated with the CYP2C19*8 allele. Mutations associated with the CYP2C19*8 allele result in poor metabolism of S-mephenytoin and tolbutamide in vitro. This type of reduced drug metabolism is characterized by deficient synthesis of cholesterol, steroids, and other lipids.


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Product Description

The CYP2C19 c.358T>C Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers and unlabeled probes necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.