COL4A4 c.3594G>A

COL4A4 c.3594G>A

The COL4A4 c.3594G>A Novallele Genotyping Assay identifies a single nucleotide change of the COL4A4 gene. Mutations of the COL4A4 gene cause Alport syndrome. Alport syndrome may result in the progressive loss of kidney function. Alport syndrome is characterized by hematuria, proteinuria, and anterior lenticonus. Another disorder caused by a COL4A4 mutation is thin basement membrane nephropathy, which can gradually progress to kidney failure.


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Product Description

The COL4A4 c.3594G>A Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.