APOE c.388T>C (UP)

APOE c.388T>C (UP)

The APOE c.388T>C (UP) Novallele Genotyping Assay identifies the APOE c.388T>C variant associated with the three common alleles, ApoE2, ApoE3, and ApoE4, of the APOE gene. The ApoE4 allele (rs429358-C + rs7412-C) is associated with increased amounts of serum cholesterol, coronary heart disease risk, and Alzheimer’s disease. Conversely, the ApoE2 allele (rs429358-T + rs7412-T) may exhibit protective features against Alzheimer’s disease.


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Product Description

The APOE c.388T>C (UP) Novallele Genotyping Assay is used to amplify and identify specific genetic polymorphisms or mutations. This assay provides scientists with a simple way to quickly genotype this locus from isolated human genomic DNA. The assay contains functionally-verified oligonucleotide primers and unlabeled probes necessary for PCR and subsequent allele identification by DNA melting. For Research Use Only. Not for use in diagnostic procedures.